Alkyl fluorides
Medchemexpress LLC Perfluorohexanoic acid | 307-24-4 | 99.9% | 314.05 | 25 G
Perfluorohexanoic acid, also known as Undecafluorocaproic acid, is a biological molecule. It is designed for research applications and not for patient use. This compound exhibits an appearance of a solid below 12°C and a liquid above 14°C, presenting as colorless to off-white.
- Biological molecule
- For research use only
- Appears solid below 12°C
- Appears liquid above 14°C
- Colorless to off-white appearance
Sigma Aldrich Fine Chemicals Biosciences Heptafluorobutyric acid 99
HEPTAFLUOROBUTYRIC9 Heptafluorobutyric acid 99
Medchemexpress LLC Neo 376 | 496921-73-4 | 99.2% | 357.88 | C20H24ClN3O | 5 MG
NEO 376 is a small-molecule research compound described as a selective modulator of 5-HT1 (serotonin), GABA, and dopamine receptors with reported antipsychotic activity. It is intended for pharmacological and neurobiological studies and is provided with analytical documentation to support research use.
- Selective modulator of 5-HT1, GABA, and dopamine receptors.
- Reported antipsychotic activity suitable for psychiatric research.
- High purity: 99.2%.
- Molecular weight 357.88 and formula C20H24ClN3O.
- Soluble in DMSO; available as 10 mM solution or as solid (small pack sizes).
- Supplied with datasheet, certificate of analysis, and safety data sheet for research use.
Medchemexpress LLC Ensartinib | 1365267-27-1 | 98.10% | 547.41 | 10 MM * 1 ML
X-376 is a potent and highly specific ALK tyrosine kinase inhibitor (TKI) with an IC50 of 0.61 nM. It is also a less potent inhibitor of MET (IC50=0.69 nM), exhibiting potent anti-tumor activity. This compound shows substantial bioavailability and moderate half-lives in vivo. Intended for research use only, animal studies indicate it is well-tolerated at effective doses without significant toxicity up to 50 mg/kg in SD rats.
- Potent ALK inhibitor (IC50: 0.61 nM)
- Inhibits MET (IC50: 0.69 nM)
- Potent in H3122, H2228, and SUDHL-1 cancer cells
- Soluble in DMSO (100 mg/mL)
- Well-tolerated in vivo with anti-tumor activity
- Stock solution storage: -80°C for 2 years, -20°C for 1 year
Medchemexpress LLC Perfluoropentanoic acid | 2706-90-3 | 98.0% | 264.05 | 10 G
Perfluoropentanoic acid (PFPeA) is a short-chain perfluorinated compound used as an indicator of perfluorinated compound pollution in ecosystems. It has shown certain toxicity in mice and can impact planktonic microbial communities. This product is for research use only.
- Serves as an indicator of perfluorinated compound pollution
- Exhibits toxicity to mice
- Affects planktonic microbial communities
- Available with downloadable data sheet, COA, and SDS
Medchemexpress LLC Perfluoropentanoic acid | 2706-90-3 | 98.0% | 264.05 | 25 G
Perfluoropentanoic acid (PFPeA) is a short-chain perfluorinated compound that serves as an important indicator of perfluorinated compound pollution in ecosystems. It has been observed to affect planktonic microbial communities and show certain toxicity in mice studies.
- Indicator of perfluorinated compound pollution
- Impacts planktonic microbial communities
- Can threaten water quality via microbial metabolism
- In vivo studies suggest potential for liver damage and skin inflammation
Medchemexpress LLC GluN1(356-385) | 99.95% | 3415.90 | 5 MG
GluN1 (356-385) is an antigenic peptide used against N-methyl-D-aspartate receptor (NMDAR) encephalitis. It effectively reduces the density of surface NMDAR clusters in hippocampal neurons. This peptide can be utilized to investigate the pathogenesis of anti-NMDAR encephalitis.
- Antigenic peptide against N-methyl-D-aspartate receptor (NMDAR) encephalitis.
- Reduces the density of surface NMDAR clusters in hippocampal neurons.
- Useful for studying the pathogenesis of anti-NMDAR encephalitis.
- Purity of 99.95%.
Medchemexpress LLC Perfluoropentanoic acid | 2706-90-3 | 98.0% | 264.05 | 1 G
Perfluoropentanoic acid (PFPeA) is a short-chain perfluorinated compound used as an important indicator of perfluorinated compound pollution in ecosystems. It exhibits certain toxicity to mice and is intended for research use only.
- Short-chain perfluorinated compound.
- Indicator of perfluorinated compound pollution.
- Exhibits toxicity to mice, affecting liver, skin, and immune cells.
- Can impact planktonic microbial communities and water quality.
- Increases serum and urine concentrations after topical application.
- Alters gene expression related to lipid metabolism and inflammation.
Cambridge Isotope Laboratories 2H 2H 3H 3H-Perfluorohexanoic acid (3 3 FTCA) (unlabeled) 100 ug/mL in methanol 1 2 mL
2H 2H 3H 3H-Perfluorohexanoic acid (3 3 FTCA) (unlabeled) 100 ug/mL in methanol 1 2 mL
Strem, An Ascensus Company CAS# 2043-47-2. 10g. 1H,1H,2H,2H-Perfluorohexan-1-ol, 99%. MFCD00039543
CAS# 2043-47-2. 10g. 1H,1H,2H,2H-Perfluorohexan-1-ol, 99%. MFCD00039543. Molecular Weight: 264.09. Molecular Formula: F(CF2)4CH2CH2OH. Color/form: colorless liq. Strem# 09-6085. http://www.strem.com/catalog/v/09-6085/
Medchemexpress LLC BAY-678 | 675103-36-3 | 99.59% | 400.35 | 50 MG
BAY-678 is an orally bioavailable, highly potent, selective, and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. It is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC). For research use only; not sold to patients.
- Orally bioavailable
- Highly potent and selective inhibitor of human neutrophil elastase (HNE)
- Cell-permeable
- IC50 of 20 nM (HNE)
- Ki value for MNE is 700 nM
- Fourth-generation HNE inhibitor
- More than 2,000-fold selectivity in a panel of 21 serine proteases
- Reveals significant efficacy in preclinical models of ALI and lung emphysema, demonstrating anti-inflammatory and anti-remodeling mode of action
- Shown significant beneficial pulmonary hemodynamic and vascular effects in models of PAH in rats and mice